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Biotech::Trekker Trekking Through the World of Biotech {created 11 October 2002} |
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Stephan Leaves TGen and Moves to California
Arizona needs all the 21st century brains it can get; therefore, I sure hope Arizona's politicians have paid close attention to Ken Alltucker's report about Dietrich Stephan leaving TGen. Dietrich is going to California because it has investors willing to make 21st century investments. Dr. Stephan is a follower of "smart" money and that meant he needed to exit Arizona. I remain firm in my belief that if Arizona's bioscience efforts fail, it won't be because of our scientists; it will be because of Arizona's void of 21st century political leadership. Kudos to California! By the way... Dietrich Stephan is the co-founder and Chief Science Officer of Redwood Shores, CA-based Navigenics. Navigenics has an excellent Genomics 101 resource. [14 August 2008, top] |
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Strong Demand for Illuminia Shares
Illumina Inc. issued a press release stating the following: "The underwriter of the public offering of the Company's common stock fully exercised its option to purchase up to 525,000 additional shares. A total of 4,025,000 shares were sold to the public at a public offering price of $87.50 per share, raising net proceeds to the Company of approximately $342.6 million. Goldman, Sachs and Co. acted as the sole manager of the offering." Kudos to San Diego-based Illuminia, Inc. [13 August 2008, top] |
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Columbia's Pe'er/Bussemaker Lab for Systems Biology
Kudos to Columbia University for the establishing the Pe'er/Bussemaker Lab for Systems Biology.
"Systems and computational biology is the meeting point between
modern molecular biology and new research techniques emerging
from the engineering, computer science, chemistry, mathematics,
statistics and physics fields. It has the potential to allow
scientists to pose limitless questions about how our cells work
and issues related to general human health: the study of gene
networks, analysis of protein shapes, prediction of biological
function and understanding how a cell processes signals."
Scientists are learning how to "probe the state of a cell." Here is a quote from the Pe'er in Pe'er/Bussemaker.
"Interdisciplinary collaborative science will make our science
better and advance quicker towards grand challenges such as a
systems-level understanding of how our cells work and even
toward a cure for cancer."
Dana Pe'er is a cofounder of the lab and an assistant professor of biological sciences at Columbia University. Columbia.edu::Scientists Open Columbia's New Computational Biology Lab [09 August 2008, top] |
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Keeping an Eye on Beike Biotechnology
I learned about Beike Biotechnology today. Beike was founded with capital from Beijing University, Hong Kong University of Science and Technology and Shenzhen City Hall. It is also supported with funds from the China State National Fund. Beike's motto: Tomorrow's Treatments, Today.
"Beike is a controversial company because it has already begun
treating patients with injections of stem cells, usually a
combination of umbilical cord cells and stem cells derived
from each patient. Beike claims to treat over 250 patients
per month, a total of more than 3,000 so far. Approximately
70% to 80% of the patients report themselves satisfied with
their treatments, and the treatments have the ability to produce
at least some therapeutic effect in 86% of its patients,
according to statistics provided by Beike.
"Beike has not submitted its techniques to the rigors of a
double-blind clinical test. Nor has it done the otherwise
necessary animal testing. Nevertheless, the company points
to its success with the majority of its patients as sufficient
proof that its stem cell therapies are a valuable addition to
the medical arsenal."
"Beike charges its patients between $20,000 and $30,000 for
several rounds of stem cells injections, which it says can
help cure diseases such as Alzheimer's, atoxia, heart conditions,
multiple sclerosis, optic nerve hypoplasia, and spinal muscular
atrophy . Although most patients come from China, its therapies
draw significant numbers of patients from the West."
BeikeBiotech.com:: Home Page [06 August 2008, top] |
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ArizonaBioBasics.com Must Be Kept Current
I sent the following as a Letter to the Editor of the Arizona Republic on 4 August 2008. In addition, I posted it to my AzCentral.com blog on August 5th.
[05 August 2008, top] |
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Illimunia To Sell 3.5 Million Shares
Secondary stock offerings are rare these days, but San Diego-based Illimunia is going to raise some cash by selling 3.5 million shares. On 4 August 2008, shortly after Illuminia announced the secondary offering, ILMN was at $90.55, giving the company a market value of approximately $5.18 billion. In a nutshell, the offering will increase the number of ILMN shares by about six percent. ILMN hit an all-time high of $95.50 on 31 July 2008.
[04 August 2008, top] |
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Isotechnika Market Value Cut in Half
On 21 July 2008, Ken Alltucker posted an item titled "Roche-Genentech deal has Arizona lesson" to his Biotech and Health blog at AzCentral.com. The Biotech Trekker posted the following comment. Another Roche induced Arizona lesson... Take a peek at Isotechnika (ISA.TO) today (July 22): down 50+% because "Roche gives up global rights to voclosporin for organ transplants." Canadian-based Isotechnika tried to put a positive twist on the news, but Wall Street said "No Way!" Isotechnika attempted to make Scottsdale its U.S. headquarters in 2003, but the attempt went belly-up in 2006. [22 July 2008, top] |
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Poste To Lead ASU's Complex Adaptive Systems Initiative
George Poste is a superstar and it is no surprise that ASU is increasing his responsibilities. Michael Crow, ASU's President, was quoted in the press release stating the following.
"Dr. Poste's extensive experience and broad-based scientific
acumen has enabled the Biodesign Institute to align large,
interdisciplinary teams against critical societal challenges,
producing substantial progress on new approaches to personalized
medicine, alternative energy, improved diagnostic devices and
new vaccine technologies. I have asked him to help me expand
this successful model to other university research programs."
The ASU press release also contained the following.
"The immediate goals of this new integration effort are to
increase research competitiveness in three of the most
exciting emerging fields of science: synthetic biology;
sensor technologies; and health care informatics."
I like the following phrase... "intellectual fusion." Biodesign.ASU.edu::Arizona State University announces new initiative leveraging intellectual fusion to revolutionize university research [17 July 2008, top] |
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TGen Gets $1.99M Supercomputing Grant
When it comes to computing power, 21st century biologists will always need more, more, more. Phoenix-based TGen announced that the NIH has awarded it with a $1.99 million grant to "enhance its supercomputing capabilities." Ed Suh, TGen's CIO, was quoted in the TGen press release saying:
"In today's genomic research environment, high-throughput
instruments allow scientists to collect increasingly large
amounts of data. This scalable computing system will allow
TGen and ASU scientists to explore those large volumes of
complex data more thoroughly and at an accelerated pace."
Dan Stanzione, Director of ASU's High Performance Computing Initiative, was quoted in the TGen press release saying:
"The success of TGen and ASU scientists to date has come at
the sacrifice of time. However, individuals affected with
disease do not have the luxury of time. The parallel
cluster-computing system will optimize TGen and ASU
researchers' ability to meet their data analyses and
systems modeling needs, and hopefully accelerate timely
and effective discovery toward improved human health"
Happy supercomputing to TGen and ASU! TGen.org::TGen Awarded $1.99 Million Grant to Advance Highly Parallel Supercomputing [17 July 2008, top] |
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Keeping an Eye On Pacific Biosciences
The Wall Street Journal reported on a company named Pacific Biosciences. The following was copied from the "About" webpage at PacificBiosciences.com.
"Pacific Biosciences (PacBio), headquartered in Menlo Park, CA,
is a startup biotechnology company developing a transformative
single-molecule, real-time (SMRT[tm]) DNA sequencing platform.
PacBio's goal is to commercialize SMRT DNA sequencing technology,
eventually enabling sequencing of individual genomes as part of
routine medical care."
PacBio was funded in 2004 and the following was copied from its "History" webpage.
"In 2005, the NHGRI (National Human Genome Research Institute)
awarded PacBio an Advanced Sequencing Technology Award grant
of $6.6 million for development of technology leading to the
$1000 genome, the largest grant of any company applying at
any level."
PacificBiosciences.com::Single Molecule Real Time [15 July 2008, top] |
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Ivy Foundation Grants $3 Million To TGen
The Biotech Trekker sent the following as a Letter to the Editor of the Arizona Republic on 11 July 2008. It was also posted to his AzCentral.com blog on 12 July 2008.
Since this blog is on the web, the value of this posting is extended thanks to the power of the hyperlink. TGen.org::Ivy Foundation Funds New Brain Cancer Research Consortium [11 July 2008, top] |
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Slashdotters Interviewing Aubrey de Grey
On 9 July 2008, Slashdot.org created a posting in which Slashdotters can submit questions to Aubrey de Grey. The questions are piling up... The Biotech Trekker referenced De Grey on an AzCentral.com posting three days ago on June 6th. Interviews.Slashdot.org::Ssk Aubrey de Grey About Longevity Research [09 July 2008, top] |
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"80 is the new 60" Phrase is Getting Old
There was an AzCentral.com posting titled "80 is the new 60" and I'm getting tired of hearing this old phrase. The Biotech Trekker, via the Gerald9588 user name, posted the following comment. posted by Gerald9588 on Jul 6, 2008 at 07:39 AM Some of us think there's a chance Aubrey de Grey might be right.... "Do you want to live forever?" http://www.technologyreview.com/Biotech/14147/ de Grey is a computing guru; therefore, he fully understands the power of high-performance computing systems. In addition, he married a genetics guru who is two decades older than him. de Grey is a sponge; therefore, he has become an expert in genetics. Hmmm... de Grey has been quoted saying that the first person to live to a 1,000 is currently sixty-something years young. Only time will tell. TechnologyReview.com::Do you want to live forever? [06 July 2008, top] |
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Hippocratic Oath for Scientists?
I've been a long-time member of the CPSR (Computer Professionals for Social Responsibility). Most computer professionals follow a strict code of ethics (at least when it comes to computing), and I suspect most scientists are ethically grounded (at least scientifically). ScienceBlogs.com::Hippocratic Oath for Scientists? [05 July 2008, top] |
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DARPA "Urgently Needs" Fracture Putty
DARPA has issued a RFP for "Fracture Putty."
"DARPA seeks to develop a dynamic putty which, when packed
in/around a compound bone fracture, provides full load-bearing
capabilities within hours, creates an osteoconductive bone-like
internal structure, and degrades over time to harmless resorbable
by-products as normal bone regenerates."
DARPA states: "More effective methods for treatment of skeletal trauma are urgently needed."
"Fracture Putty represents the ultimate convergence of
materials science, mechanics, and orthopedics. We want
to hear from potential performers with expertise in
chemistry, biomaterials, adhesives, mechanics, theoretical
modeling of dynamic systems under complex mechanical stress,
biology of bone, animal models of bone trauma, clinical
orthopedics and orthopedic surgery, and engineering."
FBO.gov::Fracture Putty [27 June 2008, top] |
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3 U.S. Companies Join the 1000 Genomes Project
"1000 Genomes" was started in on 22 January 2008 to "produce the most detailed map of human genetic variation to support disease studies."
"An international research consortium has been formed to
create the most detailed and medically useful picture to
date of human genetic variation. The 1000 Genomes Project
will involve sequencing the genomes of at least a thousand
people from around the world. The project will receive major
support from the Wellcome Trust Sanger Institute in Hinxton,
England, the Beijing Genomics Institute Shenzhen in China
and the National Human Genome Research Institute (NHGRI),
part of the National Institutes of Health (NIH)."
On 11 June 2008, Illuminia Inc. issues a press release announcing "it is among three firms to have pioneered the development of new sequencing technologies and joined the 1000 Genomes Project. The new participants are: Illumina Inc., San Diego, Calif.; 454 Life Sciences, a Roche company, Branford, Conn.; and Applied Biosystems, an Applera Corp. business, Foster City, Calif." 1000Genomes.org::A Deep Catalog of Human Genetic Variation [11 June 2008, top] |
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Stem Cells Used To Fight RDEB
University of Minnesota researchers--in collaboration with Angela Christiano, professor of molecular dermatology and genetics and development at Columbia University Medical Center, and investigators at Asahikawa Medical College (Asahikawa, Japan), and Jefferson Medical College in Philadelphia--are having success with a patient using "experimental umbilical cord blood and bone marrow transplant."
"For toddler Nate Liao, the slightest touch and every bite of
food was painful. Nate was born with recessive dystrophic
epidermolysis bullosa (RDEB), a genetic disease that causes
skin and the lining of the digestive tract to slough off.
In young adulthood, it leads to an aggressive, inevitably
fatal skin cancer."
The United States of America is going to elect a new President later this year (November 2008). The President plays a critical role in how the federal government supports stem cell research and science. The following provides evidence of the power of stem cells.
"This is the first time physicians have approached the treatment
of RDEB from a systemic perspective, using marrow-derived stem
cells from a healthy donor to correct the underlying genetic defect.
With the infusion of stem cells, new cells that produce the missing
collagen type VII are generated throughout the body."
UMN.edu::Novel stem cell therapy gives hope to boy with rare disease [08 June 2008, top] |
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More Great News Coming From TGen
I posted the following to my AzCentral.com blog on 6 June 2008. Kudos to the Republic for today's front-page Definitely front-page news: "TGen and local biotech partner land $200 million from tiny Luxembourg" by Ken Alltucker. There is zero doubt that we are in the age of genomics and personalized medicine. Kudos to Alltucker for including the following quote by Jan Lesher (director of the Arizona Department of Commerce): "It shows we are a location to be reckoned with worldwide." The following quote was posted to Philanthromedia.org by Dr. Jeffrey Solomon: "I believe that an investment in personalized medicine will have exponentially greater social benefit in the coming decades." I guess so does tiny Luxembourg. [06 June 2008, top] |
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TGen Making Progress with GDC-0449
On 28 May 2008 (my 51st birthday), I posted the following to my blog at AzCentral.com. I get upset every time the Arizona Republic puts sports on the front-page. Sports has its own section and it should never (and I never say "never") be front-page news; therefore, I was happy to see front-page space allocated for TGen. The 21st century is the "Age of Genomics" and TGen is going to make significant contributions/discoveries. The Valley of the Sun got lucky when TGen (and the International Genomics Consortium) decided to make Arizona home. Kudos to the Arizona Republic for making TGen front-page news. AzCentral.com::Unlike Sports, TGen Belongs on Page A-1 [Extra] My posting referenced a front-page story titled "'Dramatic results' for cancer drug Tumors shrinking, TGen researchers report." The experiement drug is GDC-0449. As of 2 June 2008, the Arizona Republic article had zero comments attached to it. [02 June 2008, top] |
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Biology + Computing + Robotics = The Future
Biology, computing and robotics--what a powerful combination.
"University of Pittsburgh and Carnegie Mellon University
brain-machine researchers have successfully implanted
tiny sensors in two monkeys that enable them to control
a mechanical arm using only their thoughts."
It is only a matter of time...
"The research suggests that brain-controlled prosthetics,
while still impractical, are within reach.
NYTimes.com::Monkeys Think, Moving Artificial Arm as Own [02 June 2008, top] |
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Biotech Alive in Chandler Thanks to Covance
Biotech is alive in Chandler, Arizona, thanks in part to Covance Inc. Covance is a Princeton, New Jersey-based "drug development services company" whose stock trades on the NYSE under the symbol CVD. On 2 May 2008, CVD closed at $83.88. Local news sources reported the following.
"Covance officials marked the final phase of construction on
their controversial $100 million drug-testing laboratory with
an invitation-only ceremony and tour guarded under tight security
Thursday morning."
"The facility, representing the largest capital expenditure in the
company's history, could eventually employ up to 2,000 people,
including many highly paid, white-collar professionals such as
scientists, researchers and managers."
"The facility has an area of 288,000 square-feet."
On 28 April 2008, Covance reported "1Q08 Earnings Growth of 22.3% to $0.73 Per Share; 15.1% Revenue Growth; Record Operating Margin of 15.2%; 20.1% Backlog Growth." The Biotech::Trekker says "Welcome Covance!" [03 May 2008, top] |
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Google Invests In Navigenics
The last posting to the Biotech Trekker for 2007 was on December 22nd and it was titled: "Keep An Eye On Navigenics." I posted the following to my AzCentral.com blog on 21 April 2008. Google Invests in Navigenics On 18 April 2008, BusinessWeek.com has posted an article about Google, Inc. investing in Navigenics. Redwood Shores, CA-based, Navigenics was co-founded by Dietrich Stephan of the Phoenix-based Translational Genomics Research Institute (TGen). I think Google established operations in the Valley of the Sun in large part thanks to TGen and the Biodesign Institute at ASU (and the Crowation of ASU). Go Biogoogle! BusinessWeek.com::Google Wants to Index Your DNA, Too [21 April 2008, top] |
Autologous Stem Cell Therapy for Dilated Cardiomyopathy
[2008.04.17]
Aastrom Biosciences closed up 30% today after the company
announced "encouraging clinical data reported from Aastrom's
first EU compassionate use cardiac patients." It should be
noted that "patients" equals two. The patients have been
treated with ASTM's "autologous stem cell therapy for dilated
cardiomyopathy (DCM), a type of severe chronic heart failure."
The 30% gain doesn't mean anything because these shares could
fall 30% (or more) tomorrow.
From the press release.
[patient one: 74-year-old male]
"Prior to the CRC treatment his left ventricular ejection
fraction was 10% (the percentage of blood pumped out of
the heart with each contraction), below the normal range
of 60-75% for a typical healthy person. After the CRC treatment
and upon discharge from the hospital in January 2008, this
patient's ejection fraction had improved to 25-30% and clinical
improvement of his heart failure stage had been noted."
[patient two: 69-year-old female]
"Prior to the CRC treatment her ejection fraction was 25-30%,
and upon discharge from the hospital in February 2008 her
ejection fraction had improved to 45%."
The quality of a drug is a function of many things--age and gender are two of those things. What if...? [18 April 2008, top] |
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Arizona Republic Reports On TGen
Ken Alltucker did a nice job reporting about TGen in the Business Section of the 16 April 2008 Arizona Republic.
"[...], with TGen competing for a dwindling supply of federal,
state and private dollars to pursue its medical advancements.
Monies are getting tougher to obtain; therefore the state of Arizona is going to have to stay in the batter box and continue supporting TGen's bioscience efforts.
"Over the past five years, TGen has pursued cutting-edge research
for such diseases as pancreatic cancer and Alzheimer's, spun off
several private companies and secured millions in federal and state
grants. The research group's $46 million lab anchors downtown
Phoenix's biomedical campus, and it has attracted some of the
nation's top scientists."
Beyond any doubts, TGen has a collection of outstanding scientists.
"With 258 employees spread across locations in Phoenix, Scottsdale
and Flagstaff, [...]"
258 is not a large workforce, but is a lot more than zero.
"(TGen's) scientists made a leap of faith in us, and we made a
leap of faith in you."--Councilman Greg Stanton
Investing in the future is always a "leap of faith." TGen's leap of faith in Arizona is vastly greater than Arizona's "leap of faith" in TGen.
"TGen has put us on the map in ways we certainly were not on the
map until TGen came here." said Rob Melnick, associate vice president
for economic affairs and public policy at ASU. "Big science is going
on in Phoenix."
Keyphrase: "Big Science." TGen will do big things if Arizona doesn't bail on them. [Extra] A poster on AzCentral.com made a comment about TGen being a joke. The posting annoyed me so I posted the following comment. To Tedtod: TGen is not a joke, but Arizona's political system is. TGen has done good stuff since moving to Arizona despite the fact that our state is nearly void of 21st century leaders. Go TGen, go Biodesign Inst. at ASU, go BIO5 at UA, go TGen North. The future is supercomputing, biotech, nanotech, robotics -- with or without Arizona. [16 April 2008, top] |
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Stem Cells Nearing Commercialization?
The information in this posting was obtained from Portfolio.com via MyYahoo.com. Portfolio.com wrote.
"Robert Klein, director of the California Institute for Regenerative
Medicine, is saying that fresh heart and liver cells derived from
stem cells may be ready for testing in humans within 18 months."
Here is some more timeline data.
"Safety tests for using stem cells to treat paralysis could start
within a year; tests for stem cells that replace damaged retinas
could start in two years. Later will come stem-cell trials to
replace bone and cartilage and to better target bone-marrow
transplants to treat leukemia."
Stem cells can provide benefits today--2 April 2008.
"Scientists are poised right now to use stem cells to test for
toxicity in drugs being developed. Researchers hope to replace
animal testing, which is notoriously unreliable, with human
stem cells to determine whether or not a candidate medication
is safe."
James Thompson is a stem cell guru; therefore, the Biotech Trekker thinks we should listen to what he has to say.
"Thompson wasn't optimistic about the near-term outlook for
stem-cell-based treatments--until recently. 'The field is
moving very fast now. I'm now thinking it is time to start
thinking seriously about commercialization.'"
ISSCR.org::International Society for Stem Cell Research [02 April 2008, top] |
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Gateway Community College Might Build Wet Labs
Gateway Community College (GWCC) is one of the 10 colleges that comprises the Maricopa County Community College District (MCCCD). GWCC has one huge thing going for it: Location, Location, Location. It is located across the street from Sky Harbor Intl. Airport, it has a light-rail stop, it has bus services, and it is located between downtown Phoenix, downtown Tempe, and it is not too far away from Scottdale's SkySong. The Biotech Trekker is happy to see that GWCC might be building a multi-million dollar wet lab. The lab will be at least 5,000 square feet in area. Go Gateway CC! [29 March 2008, top] |
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Illumina's Genome Analyzer Works
Bioteck Trekker is a tiny Illumina shareholder. Illumina Inc. announced that "scientists at the Company have sequenced the genome of an anonymous African male (Yoruba from Ibadan, Nigeria), using the Genome Analyzer. Sequencing of this HapMap sample was conducted internally and marks the first human genome sequence generated exclusively with paired reads of 35 to 50 bases in length. Leveraging recent system improvements that increase the throughput and improve the accuracy of the Genome Analyzer, Illumina scientists were able to complete this project in a matter of weeks. More than 95 percent of production runs generated high-quality data with an average of over three billion bases (three Gb) per run. This achievement establishes the direct utility of Illumina's sequencing technology for accurately sequencing large and complex genomes." We have entered into the age of genomics. An Illumina scientist is quoted saying.
"Making whole human genome sequencing routine will enable the
study of natural human variation all over the world, and enable
the use of medical sequencing at the whole genome level to unravel
the full spectrum of mutations, which give rise to cancer.
FBO.gov:: 66 -- BeadXpress System [29 March 2008, top] |
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Huge Thank You to Diane and Bruce Halle
The Biotech Trekker wants to extend a huge Thank You to Diane and Bruce Halle for their $350,000 gift to the Barrow Neurological Institute at St. Joseph's Hospital and Medical Center for neuro-oncology research. For almost eight years I was an employee at Discount Tire Company, which was founded by Bruce Halle in 1960. Discount Tire Company is a great American company and it has helped many of its employees realize their American dreams. Diane and Bruce Halle are cooler than cool and they are great Americans. [21 March 2008, top] |
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Orthologic Announces Stock Repurchase Program
Tempe-based Orthologic announced it will implement a stock repurchase program.
"The Company announced that its Board of Directors has approved
a stock repurchase program for up to five percent of its currently
outstanding common shares. The shares may be repurchased from time
to time in open market transactions or privately negotiated
transactions at the Company's discretion, subject to market
conditions and other factors. At February 29, 2008, there were
approximately 41.8 million shares of common stock outstanding."
A five percent buyback would approximate two million OLGC shares. Orthologic continues to "burn cash," but the company does have cash to burn.
"Orthologic "began 2007 with $70.2 million in cash and
investments and ended the year with $60.6 million in
cash and investments, a net change of $9.6 million.
For 2008, the Company forecasts a cash burn of
$16.0 million to $18.0 million."
OLGC closed at $0.97 on 3/4/2008. [05 March 2008, top] |
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AzBiotech.net Domain Name Lives Another Year
The AzBiotech.net domain name was created on 3 April 2003 at 14:46:03. The AzBiotech.net domain name has been renewed for another year and it now expires on 3 April 2009 at 11:46:02. The AzBiotech.net homepage was created on 12 December 2002. [25 February 2008, top] |
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Abraxis Bioscience Knows TGen's a Bioleader
TGen Keeps The Good News Flowing On 29 January 2008, TGen announced they received a $6.5 million grant to support an internship program. What an excellent opportunity for Arizona's young people (and for those wishing to re-career). On 1 February 2008, Ken Alltucker did a great job reporting on TGen receiving a $21.5 million investment by LA-based Abraxis Bioscience. The CEO of Abraxis has made it clear that he believes TGen is a winner--he's a smart CEO. Go TGen! TGen + Biodesign Institute at ASU + BIO5 at UA + TGen North at NAU = 21st century survival Plus, we cannot ignore what ASU is doing with respect its High Performance Computing Initiative and the fact that we have a leading 21st century Informatics company named Google hanging out in Arizona. [04 February 2008, top] |
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Human Cloning Is Going To Happen
On 2 February 2008, at 11:04am, Biotech Trekker posted a comment about human cloning to AzCentral.com. My comment was to Ken Alltucker's "Biotech and Health" blog and it was in response to a posting titled "Ban human cloning in Arizona?" Human cloning is going to happen with or without Arizona (and with or without the United States of America). Arizona has been building a strong bioscience foundation and this is not the appropriate time to take away any tools that might benefit Arizona scientists and technologists. Go ahead and start making easier and easier for scientists to be criminals, then let's see how Arizona fares in our future worlds of supercompuing/21st century informatics, biotech, nanotech and robotics. There is "An Act Amending title 36, Arizona Revised Statutes, by adding chapter 14; relating to human cloning" that Arizona politicians might act on. AzLeg.gov:: SB 1208 [04 February 2008, top] |
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TGen Gets $6.5 Million Grant For Internship Program
More good news coming out of Phoenix-based TGen.
"Helios Education Foundation, the largest education-focused
foundation serving Arizona and Florida, is providing a grant
of $6.5 million to the Translational Genomics Research Institute
(TGen) to support the Helios Scholars Program, an internship
program at TGen, for the next 25 years. Each summer, 45 high-school,
undergraduate, and graduate students come to TGen for an introduction
to high-tech bioscience research."--TGen press release
Go TGen! TGen.org:: Helios Education Foundation Invests $6.5 Million in New Partnership With TGen [01 February 2008, top] |
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Kudos To UA's BIO5
Headline from the Tucson Citizen: "$50M grant solidifies UA's bioscience position." Kudos the UA BIO5! In a nutshell, the UA-led iPlant Collaborative will "develop a centralized database of research information on plant biology and offer researchers the tools needed to solve the major science problems they face." The NSF grant is for 5-years with UA getting 79% of the $50 million and ASU getting 4%. One item that shouldn't be ignored is that 16% of the grant goes to the Cold Spring Harbor Laboratory in New York. This is a great "connection" for the state of Arizona. Arizona's governor was quoted saying.
"Arizona's future lies in innovation in areas like the biosciences,
and we are tremendously proud that the National Science Foundation
has chosen Arizona to chart a new course in plant science research."
Again, "Kudos" to BIO5 at the University of the Arizona. [Extra] Here are a couple quotes from Dan Stanzione, Director of ASU's High Performance Computing Initiative.
"Our role is to support the plant scientists in implementing
their vision for the iPlant cyberinfrastructure. We are
providing the large-scale storage, high-end computing power
and expertise in applying supercomputing as part of the
cyberinfrastructure."
"Deepening our knowledge in plant science is critically important
in confronting many of our global challenges. Food production,
energy production, environmental sustainability, the development
of biofuels and more effective medicines, dealing with climate
change -- all of these hinge on making new discoveries in
plant biology."
Fulton.ASU.edu:: Creating cyber tools for one of nation's major scientific endeavors [31 January 2008, top] |
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Orthologic Makes Progress On AZX100
Tempe-based OrthoLogic announced that the "U.S. Food and Drug Administration (FDA) has accepted an investigational new drug (IND) application for AZX100 in dermal/hypertrophic scarring. Phase 1 human clinical trials will begin during 1Q2008." Orthologic's clinical study will basically evaluate the "safety and tolerability of escalating doses of AZX100." The following was copied from Orthologic's press release.
"Market research indicates there may be as many as 21 million
procedures performed annually in the U.S. that could produce
some form of scarring. There are currently no prescription
drugs indicated for reduction of dermal scarring marketed
in the U.S. or Europe."
OLGC closed at $1.05 on 25 January 2008. [28 January 2008, top] |
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Keep An Eye On Phoenix-Based Insys Therapeutics
This Biotech Trekker posting has been laying around for way too long...
"Insys Therapeutics, a Chicago-based biotechnology firm
that specializes in rapid development and commercialization
of drugs, said Tuesday [7 March 2006] it plans to move its
corporate headquarters and research facilities to the Valley,
creating 30 jobs within three to four years."
Insys Therapeutics, Inc. Valley of the Sun location is 10220 S. 51st St. in Phoenix, Arizona, 85044. At the start of 2008, their website consisted of nothing more than a homepage. During late-2007, Insys Therapeutics (INRX) filed for an IPO to raise $86.25 million, but I don't think they've gone public yet. InsysTherapeutics.com:: Better Patient Care Through Innovation [14 January 2008, top] |
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Iran Into Cloning Animals
The information is posting was obtained from the AP (Associated Press). Iran is into cloning and this makes sense given it wants to become a "regional high-tech powerhouse in western Asia by 2025."
[source: AP]
"Iranian scientists have reported that the country's first
cloned sheep is thriving 15 months after birth. The cloned
male sheep named Royana was born 30 September 2006."
"Mohammad Isfahani, an embryologist whose team oversaw Royana's
birth and that of its cloned predecessor, said his institute
conducted 30 successful stem cell transfers but that only two
led to birth."
Iran's other cloned sheep died shortly after being born. Isfahani was quoted saying.
[source: AP]
"We are now in the early stages of cloning a cow. It is not
important for us how many animals we clone, what is important
is that we have achieved proficiency in cloning."
As of 1 January 2008, human cloning is banned in Iran. [02 January 2008, top] |
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About the Biotech Trekker
The Biotech Trekker was started during October of 2002 and it enters 2008 with 275 postings. There are going to be a lot of postings about smart drugs, stem cells and cloning over the span of this year. Biotech Trekker Archives: 2007 | 2006 | 2005 | 2004 | 2003-2002 [01 January 2008, top] |
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Creator: Gerald Thurman
[gdt@deru.com] Created: 11 October 2002 Last Modified: Thursday, 14-Aug-2008 10:12:30 MST |